Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29AI039049-01
Application #
2076159
Study Section
Experimental Virology Study Section (EVR)
Project Start
1996-09-01
Project End
2001-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Pathology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Chang, Ming; Williams, Ocean; Mittler, John et al. (2003) Dynamics of hepatitis C virus replication in human liver. Am J Pathol 163:433-44
Polyak, S J; Khabar, K S; Paschal, D M et al. (2001) Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. J Virol 75:6095-106
Polyak, S J; Khabar, K S; Rezeiq, M et al. (2001) Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy. J Virol 75:6209-11
Sullivan, D G; Kim, S S; Wilson, J J et al. (2001) Investigating hepatitis C virus heterogeneity in a high prevalence setting using heteroduplex tracking analysis. J Virol Methods 96:5-16
Chang, M; Marquardt, A P; Wood, B L et al. (2000) In situ distribution of hepatitis C virus replicative-intermediate RNA in hepatic tissue and its correlation with liver disease. J Virol 74:944-55
Cotler, S J; Taylor, S L; Gretch, D R et al. (2000) Hyperbilirubinemia and cholestatic liver injury in hepatitis C-infected liver transplant recipients. Am J Gastroenterol 95:753-9
Neumann, A U; Lam, N P; Dahari, H et al. (2000) Differences in viral dynamics between genotypes 1 and 2 of hepatitis C virus. J Infect Dis 182:28-35
Polyak, S J; Nousbaum, J B; Larson, A M et al. (2000) The protein kinase-interacting domain in the hepatitis C virus envelope glycoprotein-2 gene is highly conserved in genotype 1-infected patients treated with interferon. J Infect Dis 182:397-404
Morishima, C; Gretch, D R (1999) Clinical use of hepatitis C virus tests for diagnosis and monitoring during therapy. Clin Liver Dis 3:717-40
Rosen, H R; Hinrichs, D J; Gretch, D R et al. (1999) Association of multispecific CD4(+) response to hepatitis C and severity of recurrence after liver transplantation. Gastroenterology 117:926-32

Showing the most recent 10 out of 17 publications