Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
3R29AI039067-02S1
Application #
2790735
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1996-07-01
Project End
2001-06-30
Budget Start
1997-07-01
Budget End
1998-06-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
Ritchie, Jenny M; Wagner, Patrick L; Acheson, David W K et al. (2003) Comparison of Shiga toxin production by hemolytic-uremic syndrome-associated and bovine-associated Shiga toxin-producing Escherichia coli isolates. Appl Environ Microbiol 69:1059-66
Thorpe, Cheleste M; Hurley, Bryan P; Acheson, David W K (2003) Shiga toxin interactions with the intestinal epithelium. Methods Mol Med 73:263-73
Golden, Neal J; Acheson, David W K (2002) Identification of motility and autoagglutination Campylobacter jejuni mutants by random transposon mutagenesis. Infect Immun 70:1761-71
Gargano, J M; Ngo, T; Kim, J Y et al. (2001) Multivalent inhibition of AB(5) toxins. J Am Chem Soc 123:12909-10
Galland, J C; Hyatt, D R; Crupper, S S et al. (2001) Prevalence, antibiotic susceptibility, and diversity of Escherichia coli O157:H7 isolates from a longitudinal study of beef cattle feedlots. Appl Environ Microbiol 67:1619-27
Wagner, P L; Acheson, D W; Waldor, M K (2001) Human neutrophils and their products induce Shiga toxin production by enterohemorrhagic Escherichia coli. Infect Immun 69:1934-7
Zhang, X; McDaniel, A D; Wolf, L E et al. (2000) Quinolone antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, and death in mice. J Infect Dis 181:664-70
Golden, N J; Camilli, A; Acheson, D W (2000) Random transposon mutagenesis of Campylobacter jejuni. Infect Immun 68:5450-3
Wagner, P L; Acheson, D W; Waldor, M K (1999) Isogenic lysogens of diverse shiga toxin 2-encoding bacteriophages produce markedly different amounts of shiga toxin. Infect Immun 67:6710-4
Thorpe, C M; Flaumenhaft, R; Hurley, B et al. (1999) Shiga toxins do not directly stimulate alpha-granule secretion or enhance aggregation of human platelets. Acta Haematol 102:51-5

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