Regulation of Osteoblast Specific Gene Expression

Leach, Robin Jean

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29AR040689-05
• Application #: 2080214
• Study Section: Physiological Chemistry Study Section (PC)
• Project Start: 1991-07-01
• Project End: 1997-06-30
• Budget Start: 1995-07-01
• Budget End: 1997-06-30
• Support Year: 5
• Fiscal Year: 1995

Institution

• Name: University of Texas Health Science Center San Antonio
• Department: Anatomy/Cell Biology
• Type: Schools of Medicine
• DUNS #: 800772162
• City: San Antonio
• State: TX
• Country: United States
• Zip Code: 78229

Publications

Johnson-Pais, T L; Leach, R J (1996) 1,25-Dihydroxyvitamin D3 and transforming growth factor-beta act synergistically to override extinction of liver/bone/kidney alkaline phosphatase in osteosarcoma hybrid cells. Exp Cell Res 226:67-74

Leach, R J; Schwartz, Z; Johnson-Pais, T L et al. (1995) Osteosarcoma hybrids can preferentially target alkaline phosphatase activity to matrix vesicles: evidence for independent membrane biogenesis. J Bone Miner Res 10:1614-24

Johnson-Pais, T L; Leach, R J (1995) Regulation of osteoblast gene expression in intratypic osteosarcoma hybrid cells. Exp Cell Res 221:370-6

Johnson-Pais, T L; Leach, R J (1992) Extinction of liver/bone/kidney alkaline phosphatase in osteosarcoma hybrid cells. Somat Cell Mol Genet 18:423-30