Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA046436-04
Application #
3458611
Study Section
Molecular Biology Study Section (MBY)
Project Start
1988-03-01
Project End
1991-06-30
Budget Start
1991-03-01
Budget End
1991-06-30
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Cold Spring Harbor Laboratory
Department
Type
DUNS #
065968786
City
Cold Spring Harbor
State
NY
Country
United States
Zip Code
11724
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Yaciuk, P; Moran, E (1991) Analysis with specific polyclonal antiserum indicates that the E1A-associated 300-kDa product is a stable nuclear phosphoprotein that undergoes cell cycle phase-specific modification. Mol Cell Biol 11:5389-97
Wang, H G; Draetta, G; Moran, E (1991) E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products. Mol Cell Biol 11:4253-65
Yaciuk, P; Carter, M C; Pipas, J M et al. (1991) Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products. Mol Cell Biol 11:2116-24
Raychaudhuri, P; Bagchi, S; Devoto, S H et al. (1991) Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes. Genes Dev 5:1200-11
Stein, R W; Corrigan, M; Yaciuk, P et al. (1990) Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity. J Virol 64:4421-7
Pietenpol, J A; Stein, R W; Moran, E et al. (1990) TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell 61:777-85
Sturm, R A; Yaciuk, P (1989) DNA cleavage by restriction endonuclease PflMI is inhibited in recognition sites modified by dcm methylation. Nucleic Acids Res 17:3615