Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA055185-04
Application #
2096398
Study Section
Experimental Immunology Study Section (EI)
Project Start
1992-12-15
Project End
1997-12-14
Budget Start
1995-12-15
Budget End
1996-12-14
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Newbound, G C; O'Rourke, J P; Collins, N D et al. (2000) Repression of tax-mediated human t-lymphotropic virus type 1 transcription by inducible cAMP early repressor (ICER) protein in peripheral blood mononuclear cells. J Med Virol 62:286-92
Lairmore, M D; Albrecht, B; D'Souza, C et al. (2000) In vitro and in vivo functional analysis of human T cell lymphotropic virus type 1 pX open reading frames I and II. AIDS Res Hum Retroviruses 16:1757-64
Albrecht, B; Collins, N D; Burniston, M T et al. (2000) Human T-lymphotropic virus type 1 open reading frame I p12(I) is required for efficient viral infectivity in primary lymphocytes. J Virol 74:9828-35
Collins, N D; D'Souza, C; Albrecht, B et al. (1999) Proliferation response to interleukin-2 and Jak/Stat activation of T cells immortalized by human T-cell lymphotropic virus type 1 is independent of open reading frame I expression. J Virol 73:9642-9
Newbound, G C; O'Rourke, J P; Collins, N D et al. (1999) Comparison of HTLV-I basal transcription and expression of CREB/ATF-1/CREM family members in peripheral blood mononuclear cells and Jurkat T cells. J Acquir Immune Defic Syndr Hum Retrovirol 20:1-10
Guyot, D J; Newbound, G C; Lairmore, M D (1998) Co-stimulation of human peripheral blood mononuclear cells with IL-2 and anti-CD3 monoclonal antibodies induces phosphorylation of CREB. Immunol Lett 61:45-52
Guyot, D J; Newbound, G C; Lairmore, M D (1998) CD2 signalling induces phosphorylation of CREB in primary lymphocytes. Immunology 95:544-52
Collins, N D; Newbound, G C; Albrecht, B et al. (1998) Selective ablation of human T-cell lymphotropic virus type 1 p12I reduces viral infectivity in vivo. Blood 91:4701-7
Andrews, J M; Oglesbee, M; Lairmore, M D (1998) The effect of the cellular stress response on human T-lymphotropic virus type I envelope protein expression. J Gen Virol 79 ( Pt 12):2905-8
Albrecht, B; Collins, N D; Newbound, G C et al. (1998) Quantification of human T-cell lymphotropic virus type 1 proviral load by quantitative competitive polymerase chain reaction. J Virol Methods 75:123-40

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