Bombesin, Cyclic Inositol Phosphates and Mitogenesis

Sekar, M C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29CA057381-05
• Application #: 2098132
• Study Section: Chemical Pathology Study Section (CPA)
• Project Start: 1992-08-01
• Project End: 1997-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of Alabama Birmingham
• Department: Pathology
• Type: Schools of Dentistry
• DUNS #: 004514360
• City: Birmingham
• State: AL
• Country: United States
• Zip Code: 35294

Publications

Tan, S; Sekar, M C (1998) Fetal and placental cyclic inositol phosphohydrolase in normoxia and hypoxia. Biol Neonate 74:253-8

Sekar, M C; Scott, E D; Sambandam, V et al. (1997) Demonstration of the presence of cyclic inositol phosphohydrolase in human urine. Biochem Mol Med 62:95-100

Sekar, M C; Sambandam, V; Grizzle, W E et al. (1996) Dissociation of cyclic inositol phosphohydrolase activity from annexin III. J Biol Chem 271:8295-9

Sekar, M C; Sambandam, V; Roy, D et al. (1995) Decreased cyclic inositol phosphohydrolase activity in hamster renal tumors and human renal cell carcinomas. Biochem Mol Med 56:104-7

Chen, P; Xie, H; Sekar, M C et al. (1994) Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement. J Cell Biol 127:847-57

Sekar, M C; Sambandam, V; McDonald, J M (1993) Bombesin and muscarinic receptor activation in rat pancreas generate cyclic inositol monophosphate: possible involvement of different phospholipase C isoenzymes. Biochem Biophys Res Commun 192:1079-85