Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA060074-04
Application #
2100688
Study Section
Endocrinology Study Section (END)
Project Start
1993-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Xing, S; Furminger, T L; Tong, Q et al. (1998) Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells. J Biol Chem 273:4909-14
Sagartz, J E; Jhiang, S M; Tong, Q et al. (1997) Thyroid-stimulating hormone promotes growth of thyroid carcinomas in transgenic mice with targeted expression of the ret/PTC1 oncogene. Lab Invest 76:307-18
Tong, Q; Ryu, K Y; Jhiang, S M (1997) Promoter characterization of the rat Na+/I- symporter gene. Biochem Biophys Res Commun 239:34-41
Smanik, P A; Ryu, K Y; Theil, K S et al. (1997) Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter. Endocrinology 138:3555-8
Xing, S; Smanik, P A; Oglesbee, M J et al. (1996) Characterization of ret oncogenic activation in MEN2 inherited cancer syndromes. Endocrinology 137:1512-9
Jhiang, S M; Sagartz, J E; Tong, Q et al. (1996) Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas. Endocrinology 137:375-8
Jhiang, S M; Fithian, L; Weghorst, C M et al. (1996) RET mutation screening in MEN2 patients and discovery of a novel mutation in a sporadic medullary thyroid carcinoma. Thyroid 6:115-21
Tong, Q; Li, Y; Smanik, P A et al. (1995) Characterization of the promoter region and oligomerization domain of H4 (D10S170), a gene frequently rearranged with the ret proto-oncogene. Oncogene 10:1781-7
Smanik, P A; Furminger, T L; Mazzaferri, E L et al. (1995) Breakpoint characterization of the ret/PTC oncogene in human papillary thyroid carcinoma. Hum Mol Genet 4:2313-8
Mazzaferri, E L; Jhiang, S M (1994) Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med 97:418-28

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