Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA063531-03
Application #
2105444
Study Section
Experimental Virology Study Section (EVR)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Damico, R; Bates, P (2000) Soluble receptor-induced retroviral infection of receptor-deficient cells. J Virol 74:6469-75
Balliet, J W; Gendron, K; Bates, P (2000) Mutational analysis of the subgroup A avian sarcoma and leukosis virus putative fusion peptide domain. J Virol 74:3731-9
Wool-Lewis, R J; Bates, P (1999) Endoproteolytic processing of the ebola virus envelope glycoprotein: cleavage is not required for function. J Virol 73:1419-26
Balliet, J W; Berson, J; D'Cruz, C M et al. (1999) Production and characterization of a soluble, active form of Tva, the subgroup A avian sarcoma and leukosis virus receptor. J Virol 73:3054-61
Damico, R; Rong, L; Bates, P (1999) Substitutions in the receptor-binding domain of the avian sarcoma and leukosis virus envelope uncouple receptor-triggered structural rearrangements in the surface and transmembrane subunits. J Virol 73:3087-94
Damico, R L; Crane, J; Bates, P (1998) Receptor-triggered membrane association of a model retroviral glycoprotein. Proc Natl Acad Sci U S A 95:2580-5
Rong, L; Gendron, K; Strohl, B et al. (1998) Characterization of determinants for envelope binding and infection in tva, the subgroup A avian sarcoma and leukosis virus receptor. J Virol 72:4552-9
Balliet, J W; Bates, P (1998) Efficient infection mediated by viral receptors incorporated into retroviral particles. J Virol 72:671-6
Rong, L; Gendron, K; Bates, P (1998) Conversion of a human low-density lipoprotein receptor ligandbinding repeat to a virus receptor: identification of residues important for ligand specificity. Proc Natl Acad Sci U S A 95:8467-72
Wool-Lewis, R J; Bates, P (1998) Characterization of Ebola virus entry by using pseudotyped viruses: identification of receptor-deficient cell lines. J Virol 72:3155-60

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