Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29CA071870-01
Application #
2115387
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1996-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Pathology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Yang, Lin; Xie, Shaozhen; Jamaluddin, Md Saha et al. (2005) Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells. J Biol Chem 280:33558-65
Manes, Thomas; Zheng, Duo-Qi; Tognin, Simona et al. (2003) Alpha(v)beta3 integrin expression up-regulates cdc2, which modulates cell migration. J Cell Biol 161:817-26
Altuwaijri, Saleh; Lin, Hui-Kuan; Chuang, Kuang-Hsiang et al. (2003) Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells. Cancer Res 63:7106-12
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Moro, L; Fornaro, M; Steger, C A et al. (2001) Regulation of MCP-3 and BRCA2 mRNA expression levels by beta(1) integrins. Exp Mol Pathol 70:239-47
Manzotti, M; Dell'Orto, P; Maisonneuve, P et al. (2000) Down-regulation of beta(1C) integrin in breast carcinomas correlates with high proliferative fraction, high histological grade, and larger size. Am J Pathol 156:169-74
Fornaro, M; Steger, C A; Bennett, A M et al. (2000) Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways. Mol Biol Cell 11:2235-49
Perlino, E; Lovecchio, M; Vacca, R A et al. (2000) Regulation of mRNA and protein levels of beta1 integrin variants in human prostate carcinoma. Am J Pathol 157:1727-34

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