Mechanisms of Drug Resistance in Pediatric Brain Tumors

Bobola, Michael S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 1R29CA071937-01
• Application #: 2115435
• Study Section: Experimental Therapeutics Subcommittee 1 (ET)
• Project Start: 1996-07-10
• Project End: 2001-06-30
• Budget Start: 1996-07-10
• Budget End: 1997-06-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Seattle Children's Hospital
• DUNS #: 048682157
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98105

Publications

Bobola, Michael S; Emond, Mary J; Blank, A et al. (2004) Apurinic endonuclease activity in adult gliomas and time to tumor progression after alkylating agent-based chemotherapy and after radiotherapy. Clin Cancer Res 10:7875-83

Silber, John R; Bobola, Michael S; Blank, A et al. (2002) The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress. Clin Cancer Res 8:3008-18