Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29CA071974-01
Application #
2115464
Study Section
Special Emphasis Panel (ZRG2-NTN (03))
Project Start
1996-09-30
Project End
2001-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Karnes Jr, W E (2000) Implications of low COX-2 expression in colorectal neoplasms with defective DNA mismatch repair. J Cell Biochem Suppl 34:23-7
Klein, I K; Ritland, S R; Burgart, L J et al. (2000) Adenoma-specific alterations of protein kinase C isozyme expression in Apc(MIN) mice. Cancer Res 60:2077-80
Weller, S G; Klein, I K; Penington, R C et al. (1999) Distinct protein kinase C isozymes signal mitogenesis and apoptosis in human colon cancer cells. Gastroenterology 117:848-57
Karnes Jr, W E; Shattuck-Brandt, R; Burgart, L J et al. (1998) Reduced COX-2 protein in colorectal cancer with defective mismatch repair. Cancer Res 58:5473-7
Karnes Jr, W E; Weller, S G; Adjei, P N et al. (1998) Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells. Gastroenterology 114:930-9