Substance abuse is on the rise in women. This increase in prevalence is disconcerting because women who abuse substances are at greater risk for a number of adverse consequences including HIV and violence. Women with schizophrenia and co-occurring substance use disorders may be at particular risk for HIV and violence because of the unique cognitive and social deficits they experience. There is, however, little or no research to support this hypothesis. Thus the primary goals of this project are: 1) to determine if women with schizophrenia and co-occurring substance use disorders are more vulnerable to HIV (e.g., engage in more high risk behaviors) and violent victimization than either women with major depression and co-occurring substance use disorders or women with substance use disorders only and no history of serious and persistent mental illness; 2) to determine if women with schizophrenia who abuse substances experience more violent victimization the women with major depression and co-occurring substance use disorders, or women with substance abuse disorders alone and no history of serious and persistent mental illness, and 3) to examine the causal sequencing between cognitive functioning, social competency, negative symptoms, and HIV risk and victimization.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DA011199-03
Application #
6174965
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Thomas, Yonette
Project Start
1998-09-30
Project End
2003-08-31
Budget Start
2000-09-01
Budget End
2001-08-31
Support Year
3
Fiscal Year
2000
Total Cost
$102,413
Indirect Cost
Name
University of Maryland Baltimore
Department
Psychiatry
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Aakre, Jennifer M; Brown, Clayton H; Benson, Kathleen M et al. (2014) Trauma exposure and PTSD in women with schizophrenia and coexisting substance use disorders: comparisons to women with severe depression and substance use disorders. Psychiatry Res 220:840-5
Bellack, Alan S; Brown, Clayton H; Thomas-Lohrman, Shannon (2006) Psychometric characteristics of role-play assessments of social skill in schizophrenia. Behav Ther 37:339-52
Bennett, Melanie E; Bellack, Alan S; Gearon, Jean S (2006) Development of a comprehensive measure to assess clinical issues in dual diagnosis patients: The Substance Use Event Survey for Severe Mental Illness. Addict Behav 31:2249-67
Gearon, Jean S; Kaltman, Stacey I; Brown, Clayton et al. (2003) Traumatic life events and PTSD among women with substance use disorders and schizophrenia. Psychiatr Serv 54:523-8
Gearon, Jean S; Nidecker, Melissa; Bellack, Alan et al. (2003) Gender differences in drug use behavior in people with serious mental illnesses. Am J Addict 12:229-41
Gearon, J S; Bellack, A S; Rachbeisel, J et al. (2001) Drug-use behavior and correlates in people with schizophrenia. Addict Behav 26:51-61
Gearon, J S; Bellack, A S (2000) Sex differences in illness presentation, course, and level of functioning in substance-abusing schizophrenia patients. Schizophr Res 43:65-70