Abstract

The goal of this study is to study directional hearing in fish, using the sleeper goby as the model. It has five aims: 1. Determine the structural polarity of sensory hair cells in each otolithic organ in 3D space using LEM and SEM. 2. Determine if individual end organs play differential roles in encoding sound direction along different planes. 3. Make structure-function relationships by dye-filling ganglion cells from which directional sensitivity had been assessed by intracellular recordings. 4. Identify any particular direction in which the fish is particularly sensitive and measure MAAs. 5. Determine the contribution of each end organ to the pattern of directional hearing.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DC003275-04
Application #
6137874
Study Section
Hearing Research Study Section (HAR)
Program Officer
Luethke, Lynn E
Project Start
1998-01-01
Project End
2002-12-31
Budget Start
2000-01-01
Budget End
2000-12-31
Support Year
4
Fiscal Year
2000
Total Cost
$100,681
Indirect Cost

  Institution

Name
University of Miami Coral Gables
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Coral Gables
State
FL
Country
United States
Zip Code
33146

  Publications

Tomchik, Seth M; Lu, Zhongmin (2005) Octavolateral projections and organization in the medulla of a teleost fish, the sleeper goby (Dormitator latifrons). J Comp Neurol 481:96-117
Lu, Z; Xu, Z; Buchser, W J (2004) Coding of acoustic particle motion by utricular fibers in the sleeper goby, Dormitator latifrons. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 190:923-38
Lu, Z; Xu, Z; Buchser, W J (2003) Acoustic response properties of lagenar nerve fibers in the sleeper goby, Dormitator latifrons. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 189:889-905
Lu, Z; Xu, Z (2002) Effects of saccular otolith removal on hearing sensitivity of the sleeper goby (Dormitator latifrons). J Comp Physiol A Neuroethol Sens Neural Behav Physiol 188:595-602
Lu, Z; Tomchik, S M (2002) Effects of a red-tide toxin on fish hearing. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 188:807-13
Lu, Z; Popper, A N (2001) Neural response directionality correlates of hair cell orientation in a teleost fish. J Comp Physiol A 187:453-65
Lu, Z; Song, J; Popper, A N (1998) Encoding of acoustic directional information by saccular afferents of the sleeper goby, Dormitator latifrons. J Comp Physiol A 182:805-15