This study will examine the role of stress, distress and bruxism in pain exacerbation in myofascial TMD. It will also evaluate the role of bruxism in moderating the efficacy of a commonly used oral appliance. The study will recruit 85 new admissions to the TMD clinic at the Univ. of Medicine and Dentistry of New Jersey (UMDNJ) who meet diagnostic criteria for myofascial TMD and who have had no prior treatment with oral appliances for facial pain. A group of 85 control subjects without any TMD will also be recruited from the non-TMD clinics at UMDNJ. To test the role of stress, distress, and bruxism in exacerbating facial pain, TMD patients and controls will complete daily diaries of stress, distress and pain for one week. At beginning of this period and exactly one week later, full-mouth dental impressions will be taken. These impressions will be used to prepare micrographs that will be examined under a scanning electron microscope. By examining changes in scratch marks between the two periods, subjects will be graded for severity of bruxism. Regression models will test the relation between stress, distress, bruxism, and facial pain. Analyses will also compare severity in bruxism in TMD patients and controls. To test the role of bruxism in treatment outcome, TMD patients will then be randomly assigned to receive either a full-coverage hard acrylic splint or palatal splint. In two followup visits over the following month, pain and disability will be assessed. Analyses will examine whether the efficacy of the active vs. palatal splint is moderated by the degree to which patients show evidence of bruxism.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DE011714-03
Application #
2713284
Study Section
Special Emphasis Panel (ZRG2-HUD-2 (02))
Project Start
1996-08-01
Project End
2001-05-31
Budget Start
1998-06-01
Budget End
1999-05-31
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Psychiatry
Type
Schools of Medicine
DUNS #
605799469
City
Newark
State
NJ
Country
United States
Zip Code
07107
Janal, Malvin N; Raphael, Karen G; Klausner, Jack et al. (2007) The role of tooth-grinding in the maintenance of myofascial face pain: a test of alternate models. Pain Med 8:486-96
Raphael, Karen G; Klausner, Jack J; Nayak, Sangeetha et al. (2003) Complementary and alternative therapy use by patients with myofascial temporomandibular disorders. J Orofac Pain 17:36-41
Marbach, J J; Raphael, K G; Janal, M N et al. (2003) Reliability of clinician judgements of bruxism. J Oral Rehabil 30:113-8
Raphael, K G; Marbach, J J; Klausner, J J et al. (2003) Is bruxism severity a predictor of oral splint efficacy in patients with myofascial face pain? J Oral Rehabil 30:17-29
Raphael, Karen G; Marbach, Joseph J; Touger-Decker, Riva (2002) Dietary fiber intake in patients with myofascial face pain. J Orofac Pain 16:39-47
Raphael, K G; Marbach, J J (2001) Widespread pain and the effectiveness of oral splints in myofascial face pain. J Am Dent Assoc 132:305-16
Raphael, K G; Marbach, J J; Klausner, J (2000) Myofascial face pain. Clinical characteristics of those with regional vs. widespread pain. J Am Dent Assoc 131:161-71
Raphael, K G; Marbach, J J (2000) Comorbid fibromyalgia accounts for reduced fecundity in women with myofascial face pain. Clin J Pain 16:29-36
Raphael, K G; Marbach, J J; Gallagher, R M et al. (1999) Myofascial TMD does not run in families. Pain 80:15-22
Dohrenwend, B P; Raphael, K G; Marbach, J J et al. (1999) Why is depression comorbid with chronic myofascial face pain? A family study test of alternative hypotheses. Pain 83:183-92

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