Project Start
1989-01-01
Project End
1993-12-31
Budget Start
1992-01-01
Budget End
1992-12-31
Support Year
4
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Newgard, C B (1994) Cellular engineering and gene therapy strategies for insulin replacement in diabetes. Diabetes 43:341-50
Becker, T C; Noel, R J; Coats, W S et al. (1994) Use of recombinant adenovirus for metabolic engineering of mammalian cells. Methods Cell Biol 43 Pt A:161-89
Newgard, C B; Hughes, S D; Quaade, C et al. (1993) Molecular engineering of the pancreatic beta-cell. J Lab Clin Med 122:356-63
Gomez-Foix, A M; Coats, W S; Baque, S et al. (1992) Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism. J Biol Chem 267:25129-34
Newgard, C B (1992) Cellular engineering for the treatment of metabolic disorders: prospects for therapy in diabetes. Biotechnology (N Y) 10:1112-20
Coats, W S; Browner, M F; Fletterick, R J et al. (1991) An engineered liver glycogen phosphorylase with AMP allosteric activation. J Biol Chem 266:16113-9
Newgard, C B; Norkiewicz, B; Hughes, S D et al. (1991) Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation. Biochim Biophys Acta 1090:333-42