Igf-II and Muscle Cell Differentiation

Rosenthal, Stephen M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29DK044181-05
• Application #: 2143595
• Study Section: Cellular Biology and Physiology Subcommittee 1 (CBY)
• Project Start: 1992-05-01
• Project End: 1997-06-30
• Budget Start: 1996-05-01
• Budget End: 1997-06-30
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of California San Francisco
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 073133571
• City: San Francisco
• State: CA
• Country: United States
• Zip Code: 94143

Publications

Silverman, L A; Cheng, Z Q; Hsiao, D et al. (1995) Skeletal muscle cell-derived insulin-like growth factor (IGF) binding proteins inhibit IGF-I-induced myogenesis in rat L6E9 cells. Endocrinology 136:720-6

Rosenthal, S M; Cheng, Z Q (1995) Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts. Proc Natl Acad Sci U S A 92:10307-11

Rosenthal, S M; Hsiao, D; Silverman, L A (1994) An insulin-like growth factor-II (IGF-II) analog with highly selective affinity for IGF-II receptors stimulates differentiation, but not IGF-I receptor down-regulation in muscle cells. Endocrinology 135:38-44

Rosenthal, S M; Brown, E J (1994) Mechanisms of insulin-like growth factor (IGF)-II-induced IGF-I receptor down-regulation in BC3H-1 muscle cells. J Endocrinol 141:69-74