Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK044332-06
Application #
2143719
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Louisville
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Louisville
State
KY
Country
United States
Zip Code
40292
Darling, D S; Gaur, N K; Zhu, B (1998) A zinc finger homeodomain transcription factor binds specific thyroid hormone response elements. Mol Cell Endocrinol 139:25-35
Zhu, G; Allende, M L; Jaskiewicz, E et al. (1998) Two soluble glycosyltransferases glycosylate less efficiently in vivo than their membrane bound counterparts. Glycobiology 8:831-40
Zhu, G; Jaskiewicz, E; Bassi, R et al. (1997) Beta 1,4 N-acetylgalactosaminyltransferase (GM2/GD2/GA2 synthase) forms homodimers in the endoplasmic reticulum: a strategy to test for dimerization of Golgi membrane proteins. Glycobiology 7:987-96
Zhang, S S; Carrillo, A J; Darling, D S (1997) Expression of multiple thyroid hormone receptor mRNAs in human oocytes, cumulus cells, and granulosa cells. Mol Hum Reprod 3:555-62
Jaskiewicz, E; Zhu, G; Bassi, R et al. (1996) Beta1,4-N-acetylgalactosaminyltransferase (GM2 synthase) is released from Golgi membranes as a neuraminidase-sensitive, disulfide-bonded dimer by a cathepsin D-like protease. J Biol Chem 271:26395-403
Jaskiewicz, E; Zhu, G; Taatjes, D J et al. (1996) Cloned beta 1,4N-acetylgalactosaminyltransferase: subcellular localization and formation of disulfide bonded species. Glycoconj J 13:213-23
Cabanillas, A M; Darling, D S (1996) Alternative splicing gives rise to two isoforms of Zfhep, a zinc finger/homeodomain protein that binds T3-response elements. DNA Cell Biol 15:643-51
Lutz, M S; Jaskiewicz, E; Darling, D S et al. (1994) Cloned beta 1,4 N-acetylgalactosaminyltransferase synthesizes GA2 as well as gangliosides GM2 and GD2. GM3 synthesis has priority over GA2 synthesis for utilization of lactosylceramide substrate in vivo. J Biol Chem 269:29227-31
Darling, D S; Carter, R L; Yen, P M et al. (1993) Different dimerization activities of alpha and beta thyroid hormone receptor isoforms. J Biol Chem 268:10221-7