Glucose Sensing in Transgenic Pancreatic Islets

Epstein, Paul N.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29DK044519-05
• Application #: 2143863
• Study Section: Metabolism Study Section (MET)
• Project Start: 1992-09-30
• Project End: 1998-09-29
• Budget Start: 1996-09-30
• Budget End: 1998-09-29
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of North Dakota
• Department: Pharmacology
• Type: Schools of Medicine
• DUNS #: 102280781
• City: Grand Forks
• State: ND
• Country: United States
• Zip Code: 58202

Publications

Kang, Y J; Chen, Y; Yu, A et al. (1997) Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity. J Clin Invest 100:1501-6

Carlson, E C; Audette, J L; Klevay, L M et al. (1997) Ultrastructural and functional analyses of nephropathy in calmodulin-induced diabetic transgenic mice. Anat Rec 247:9-19

Kang, Y J; Chen, Y; Epstein, P N (1996) Suppression of doxorubicin cardiotoxicity by overexpression of catalase in the heart of transgenic mice. J Biol Chem 271:12610-6

Xu, B; Epstein, P N (1996) Unequal potency of transgenic yeast hexokinase on pancreatic beta cell metabolism and secretion. Endocr Res 22:147-58

Voss-McCowan, M E; Xu, B; Epstein, P N (1994) Insulin synthesis, secretory competence, and glucose utilization are sensitized by transgenic yeast hexokinase. J Biol Chem 269:15814-8