Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK044533-04
Application #
2143876
Study Section
Endocrinology Study Section (END)
Project Start
1993-05-01
Project End
1998-04-30
Budget Start
1996-07-24
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Purdue University
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907

  Publications

Fan, H; Zhang, H; Pascuzzi, P E et al. (2016) Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2. Oncogene 35:715-26
Zhang, Hao; Diab, Ahmed; Fan, Huitao et al. (2015) PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis. Cancer Res 75:2363-74
Slagle, Betty L; Andrisani, Ourania M; Bouchard, Michael J et al. (2015) Technical standards for hepatitis B virus X protein (HBx) research. Hepatology 61:1416-24
Andrisani, Ourania M (2013) Deregulation of epigenetic mechanisms by the hepatitis B virus X protein in hepatocarcinogenesis. Viruses 5:858-72
Studach, Leo L; Menne, Stephan; Cairo, Stefano et al. (2012) Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein. Hepatology 56:1240-51
Wang, Wen-Horng; Studach, Leo L; Andrisani, Ourania M (2011) Proteins ZNF198 and SUZ12 are down-regulated in hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replication. Hepatology 53:1137-47
Andrisani, Ourania M; Studach, Leo; Merle, Philippe (2011) Gene signatures in hepatocellular carcinoma (HCC). Semin Cancer Biol 21:4-9
Studach, Leo; Wang, Wen-Horng; Weber, Gregory et al. (2010) Polo-like kinase 1 activated by the hepatitis B virus X protein attenuates both the DNA damage checkpoint and DNA repair resulting in partial polyploidy. J Biol Chem 285:30282-93
Santiago-Rivera, Z I; Williams, J S; Gorenstein, D G et al. (1993) Bacterial expression and characterization of the CREB bZip module: circular dichroism and 2D 1H-NMR studies. Protein Sci 2:1461-71