Calcium-Independent Phospholipase A2

Portilla, Didier

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29DK046914-04
• Application #: 2146200
• Study Section: Pathology A Study Section (PTHA)
• Project Start: 1993-08-01
• Project End: 1998-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Arkansas for Medical Sciences
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• City: Little Rock
• State: AR
• Country: United States
• Zip Code: 72205

Publications

Portilla, D; Crew, M D; Grant, D et al. (1998) cDNA cloning and expression of a novel family of enzymes with calcium-independent phospholipase A2 and lysophospholipase activities. J Am Soc Nephrol 9:1178-86

Portilla, D (1997) Carnitine palmitoyl-transferase enzyme inhibition protects proximal tubules during hypoxia. Kidney Int 52:429-37

Portilla, D; Dai, G (1996) Purification of a novel calcium-independent phospholipase A2 from rabbit kidney. J Biol Chem 271:15451-7

Schonefeld, M; Noble, S; Bertorello, A M et al. (1996) Hypoxia-induced amphiphiles inhibit renal Na+, K(+)-ATPase. Kidney Int 49:1289-96

Portilla, D; Creer, M H (1995) Plasmalogen phospholipid hydrolysis during hypoxic injury of rabbit proximal tubules. Kidney Int 47:1087-94