Fatty Acid Oxidation Complexes From E coli and Mammals

Yang, Song-Yu

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29DK047392-03
• Application #: 2146946
• Study Section: Medical Biochemistry Study Section (MEDB)
• Project Start: 1994-01-01
• Project End: 1998-12-31
• Budget Start: 1996-02-15
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Institute for Basic Research in Dev Disabil
• DUNS #: 167205090
• City: Staten Island
• State: NY
• Country: United States
• Zip Code: 10314

Publications

He, X Y; Merz, G; Yang, Y Z et al. (2000) Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism. Biochim Biophys Acta 1484:267-77

He, X Y; Merz, G; Mehta, P et al. (1999) Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17beta-hydroxysteroid dehydrogenase. J Biol Chem 274:15014-9

He, X Y; Schulz, H; Yang, S Y (1998) A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease. J Biol Chem 273:10741-6

Yang, S Y; He, X Y; Schulz, H (1995) Glutamate 139 of the large alpha-subunit is the catalytic base in the dehydration of both D- and L-3-hydroxyacyl-coenzyme A but not in the isomerization of delta 3, delta 2-enoyl-coenzyme A catalyzed by the multienzyme complex of fatty acid oxidation from Biochemistry 34:6441-7

Yang, S Y (1994) The large subunit of the pig heart mitochondrial membrane-bound beta-oxidation complex is a long-chain enoyl-CoA hydratase: 3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme. Comp Biochem Physiol B Biochem Mol Biol 109:557-66

Yang, S Y; He, X Y; Styles, J et al. (1994) Primary structure of the large subunit of trifunctional beta-oxidation complex from pig heart mitochondria. Biochem Biophys Res Commun 198:431-7