Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK047987-03
Application #
2147974
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1994-05-10
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Ferrebee, Courtney B; Li, Jianing; Haywood, Jamie et al. (2018) Organic Solute Transporter ?-? Protects Ileal Enterocytes From Bile Acid-Induced Injury. Cell Mol Gastroenterol Hepatol 5:499-522
Sultan, Mutaz; Rao, Anuradha; Elpeleg, Orly et al. (2018) Organic solute transporter-? (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis. Hepatology 68:590-598
Li, Jianing; Dawson, Paul A (2018) Animal models to study bile acid metabolism. Biochim Biophys Acta Mol Basis Dis :
Dawson, Paul A; Parini, Paolo (2018) Hepatic thyroid hormone receptor ?1 agonism: good for lipids, good for bile? J Lipid Res 59:1551-1553
Dawson, Paul A (2017) Roles of Ileal ASBT and OST?-OST? in Regulating Bile Acid Signaling. Dig Dis 35:261-266
Dawson, Paul A; Setchell, Kenneth D R (2017) Will the real bile acid sulfotransferase please stand up? Identification of Sult2a8 as a major hepatic bile acid sulfonating enzyme in mice. J Lipid Res 58:1033-1035
Dawson, Paul A (2017) Hepatic bile acid uptake in humans and mice: Multiple pathways and expanding potential role for gut-liver signaling. Hepatology 66:1384-1386
Thompson, Cayla A; Wojta, Kevin; Pulakanti, Kirthi et al. (2017) GATA4 Is Sufficient to Establish Jejunal Versus Ileal Identity in the Small Intestine. Cell Mol Gastroenterol Hepatol 3:422-446
Rao, Anuradha; Kosters, Astrid; Mells, Jamie E et al. (2016) Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice. Sci Transl Med 8:357ra122
Dawson, Paul A (2016) Toxic bile and sclerosing cholangitis: Is there a role for pharmacological interruption of the bile acid enterohepatic circulation? Hepatology 63:363-4

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