Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29ES006272-04
Application #
2155136
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1992-12-10
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Woods Hole Oceanographic Institution
Department
Biology
Type
Other Domestic Higher Education
DUNS #
001766682
City
Woods Hole
State
MA
Country
United States
Zip Code
02543
DeGroot, Danica E; Franks, Diana G; Higa, Tatsuo et al. (2015) Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists. Chem Res Toxicol 28:1176-85
Shoots, Jenny; Fraccalvieri, Domenico; Franks, Diana G et al. (2015) An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Environ Sci Technol 49:6993-7001
Odio, Camila; Holzman, Sarah A; Denison, Michael S et al. (2013) Specific ligand binding domain residues confer low dioxin responsiveness to AHR1? of Xenopus laevis. Biochemistry 52:1746-54
Bravo, C F; Curtis, L R; Myers, M S et al. (2011) Biomarker responses and disease susceptibility in juvenile rainbow trout Oncorhynchus mykiss fed a high molecular weight PAH mixture. Environ Toxicol Chem 30:704-14
Besselink, H T; Denison, M S; Hahn, M E et al. (1998) Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition. Toxicol Sci 43:161-71
Hahn, M E; Woodin, B R; Stegeman, J J et al. (1998) Aryl hydrocarbon receptor function in early vertebrates: inducibility of cytochrome P450 1A in agnathan and elasmobranch fish. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 120:67-75
Hahn, M E (1998) The aryl hydrocarbon receptor: a comparative perspective. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 121:23-53
Hahn, M E; Karchner, S I; Shapiro, M A et al. (1997) Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family. Proc Natl Acad Sci U S A 94:13743-8
Hahn, M E; Karchner, S I (1995) Evolutionary conservation of the vertebrate Ah (dioxin) receptor: amplification and sequencing of the PAS domain of a teleost Ah receptor cDNA. Biochem J 310 ( Pt 2):383-7