Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29ES007365-01A1
Application #
2156753
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
Organized Research Units
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Farrer, David G; Hueber, Sara M; McCabe Jr, Michael J (2005) Lead enhances CD4+ T cell proliferation indirectly by targeting antigen presenting cells and modulating antigen-specific interactions. Toxicol Appl Pharmacol 207:125-37
McCabe Jr, M J; Singh, K P; Reiners Jr, J J (2001) Low level lead exposure in vitro stimulates the proliferation and expansion of alloantigen-reactive CD4(high) T cells. Toxicol Appl Pharmacol 177:219-31
Whitekus, M J; Santini, R P; Rosenspire, A J et al. (1999) Protection against CD95-mediated apoptosis by inorganic mercury in Jurkat T cells. J Immunol 162:7162-70
McCabe Jr, M J; Singh, K P; Reiners Jr, J J (1999) Lead intoxication impairs the generation of a delayed type hypersensitivity response. Toxicology 139:255-64
McCabe Jr, M J; Santini, R P; Rosenspire, A J (1999) Low and nontoxic levels of ionic mercury interfere with the regulation of cell growth in the WEHI-231 B-cell lymphoma. Scand J Immunol 50:233-41
Rosenspire, A J; Bodepudi, S; Mathews, M et al. (1998) Low levels of ionic mercury modulate protein tyrosine phosphorylation in lymphocytes. Int J Immunopharmacol 20:697-707