Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29EY010697-04
Application #
2518762
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1994-09-01
Project End
1999-08-31
Budget Start
1997-09-01
Budget End
1998-08-31
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Lyons, Timothy J; Basu, Arpita (2012) Biomarkers in diabetes: hemoglobin A1c, vascular and tissue markers. Transl Res 159:303-12
Sochaski, M A; Jenkins, A J; Lyons, T J et al. (2001) Isotope dilution gas chromatography/mass spectrometry method for the determination of methionine sulfoxide in protein. Anal Chem 73:4662-7
Lyons, T J; Li, W; Wojciechowski, B et al. (2000) Aminoguanidine and the effects of modified LDL on cultured retinal capillary cells. Invest Ophthalmol Vis Sci 41:1176-80
Verzijl, N; DeGroot, J; Thorpe, S R et al. (2000) Effect of collagen turnover on the accumulation of advanced glycation end products. J Biol Chem 275:39027-31
Fountain, W C; Requena, J R; Jenkins, A J et al. (1999) Quantification of N-(glucitol)ethanolamine and N-(carboxymethyl)serine: two products of nonenzymatic modification of aminophospholipids formed in vivo. Anal Biochem 272:48-55
Jenkins, A J; Li, W; Moller, K et al. (1999) Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells. Curr Eye Res 19:137-45
Lyons, T J; Jenkins, A J (1997) Lipoprotein glycation and its metabolic consequences. Curr Opin Lipidol 8:174-80
Requena, J R; Fu, M X; Ahmed, M U et al. (1997) Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein. Biochem J 322 ( Pt 1):317-25
Fu, M X; Requena, J R; Jenkins, A J et al. (1996) The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions. J Biol Chem 271:9982-6