Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29EY011483-01
Application #
2165797
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Cowell, Brigitte A; Twining, Sally S; Hobden, Jeffrey A et al. (2003) Mutation of lasA and lasB reduces Pseudomonas aeruginosa invasion of epithelial cells. Microbiology 149:2291-9
Hobden, Jeffrey A (2003) Intercellular adhesion molecule-2 (ICAM-2) and Pseudomonas aeruginosa ocular infection. DNA Cell Biol 22:649-55
Hobden, Jeffery A (2002) Pseudomonas aeruginosa proteases and corneal virulence. DNA Cell Biol 21:391-6
Pillar, Christopher M; Hobden, Jeffery A (2002) Pseudomonas aeruginosa exotoxin A and keratitis in mice. Invest Ophthalmol Vis Sci 43:1437-44
Alionte, L G; Cannon, B M; White, C D et al. (2001) Pseudomonas aeruginosa LasA protease and corneal infections. Curr Eye Res 22:266-71
White, C D; Alionte, L G; Cannon, B M et al. (2001) Corneal virulence of LasA protease--deficient Pseudomonas aeruginosa PAO1. Cornea 20:643-6
Hobden, J A; Masinick-McClellan, S; Barrett, R P et al. (1999) Pseudomonas aeruginosa keratitis in knockout mice deficient in intercellular adhesion molecule 1. Infect Immun 67:972-5
Cowell, B A; Willcox, M D; Hobden, J A et al. (1998) An ocular strain of Pseudomonas aeruginosa is inflammatory but not virulent in the scarified mouse model. Exp Eye Res 67:347-56
Chen, L; Hobden, J A; Masinick, S A et al. (1998) Environmental factors influence P. aeruginosa binding to the wounded mouse cornea. Curr Eye Res 17:231-7
Hobden, J A; Masinick, S A; Barrett, R P et al. (1997) Proinflammatory cytokine deficiency and pathogenesis of Pseudomonas aeruginosa keratitis in aged mice. Infect Immun 65:2754-8