Antibodies as Catalysts

Hilvert, Donald M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29GM038273-05
• Application #: 3466238
• Study Section: Bio-Organic and Natural Products Chemistry Study Section (BNP)
• Project Start: 1987-04-01
• Project End: 1991-09-17
• Budget Start: 1991-04-01
• Budget End: 1991-09-17
• Support Year: 5
• Fiscal Year: 1991

Institution

• Name: Scripps Research Institute
• City: La Jolla
• State: CA
• Country: United States
• Zip Code: 92037

Publications

Debler, Erik W; Müller, Roger; Hilvert, Donald et al. (2009) An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket. Proc Natl Acad Sci U S A 106:18539-44