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Tibbs, Zachary E; Rohn-Glowacki, Katie Jo; Crittenden, Frank et al. (2015) Structural plasticity in the human cytosolic sulfotransferase dimer and its role in substrate selectivity and catalysis. Drug Metab Pharmacokinet 30:3-20
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Wang, Ting; Cook, Ian; Falany, Charles N et al. (2014) Paradigms of sulfotransferase catalysis: the mechanism of SULT2A1. J Biol Chem 289:26474-80
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Rohn-Glowacki, Katie Jo; Falany, Charles N (2014) The potent inhibition of human cytosolic sulfotransferase 1A1 by 17?-ethinylestradiol is due to interactions with isoleucine 89 on loop 1. Horm Mol Biol Clin Investig 20:81-90
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Cook, Ian; Wang, Ting; Almo, Steven C et al. (2013) The gate that governs sulfotransferase selectivity. Biochemistry 52:415-24
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Leyh, Thomas S; Cook, Ian; Wang, Ting (2013) Structure, dynamics and selectivity in the sulfotransferase family. Drug Metab Rev 45:423-30
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Cook, Ian; Wang, Ting; Falany, Charles N et al. (2013) High accuracy in silico sulfotransferase models. J Biol Chem 288:34494-501
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Falany, Charles N; Rohn-Glowacki, Katie Jo (2013) SULT2B1: unique properties and characteristics of a hydroxysteroid sulfotransferase family. Drug Metab Rev 45:388-400
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Cook, Ian; Wang, Ting; Almo, Steven C et al. (2013) Testing the sulfotransferase molecular pore hypothesis. J Biol Chem 288:8619-26
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Rohn, Katie Jo; Cook, Ian T; Leyh, Thomas S et al. (2012) Potent inhibition of human sulfotransferase 1A1 by 17ýý-ethinylestradiol: role of 3'-phosphoadenosine 5'-phosphosulfate binding and structural rearrangements in regulating inhibition and activity. Drug Metab Dispos 40:1588-95
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Salman, Emily D; He, Dongning; Runge-Morris, Melissa et al. (2011) Site-directed mutagenesis of human cytosolic sulfotransferase (SULT) 2B1b to phospho-mimetic Ser348Asp results in an isoform with increased catalytic activity. J Steroid Biochem Mol Biol 127:315-23
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