Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM047431-05
Application #
2184858
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1992-06-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1998-05-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
North Carolina State University Raleigh
Department
Biochemistry
Type
Schools of Earth Sciences/Natur
DUNS #
City
Raleigh
State
NC
Country
United States
Zip Code
27695
Lieberman, David V; Hardin, Charles C (2004) Extraction of information on the buildup and consumption of reactive intermediates from quadruplex DNA assembly time courses. Biochim Biophys Acta 1679:59-64
Hardin, C C; Sneeden, J L; Lemon, S M et al. (1999) Folding of pyrimidine-enriched RNA fragments from the vicinity of the internal ribosomal entry site of hepatitis A virus. Nucleic Acids Res 27:665-73
Brown, J C; Brown 2nd, B A; Li, Y et al. (1998) Construction and characterization of a quadruplex DNA selective single-chain autoantibody from a viable motheaten mouse hybridoma with homology to telomeric DNA binding proteins. Biochemistry 37:16338-48
Brown 2nd, B A; Li, Y; Brown, J C et al. (1998) Isolation and characterization of a monoclonal anti-quadruplex DNA antibody from autoimmune ""viable motheaten"" mice. Biochemistry 37:16325-37
Hardin, C C; Corregan, M J; Lieberman, D V et al. (1997) Allosteric interactions between DNA strands and monovalent cations in DNA quadruplex assembly: thermodynamic evidence for three linked association pathways. Biochemistry 36:15428-50
Schultz, D E; Hardin, C C; Lemon, S M (1996) Specific interaction of glyceraldehyde 3-phosphate dehydrogenase with the 5'-nontranslated RNA of hepatitis A virus. J Biol Chem 271:14134-42
Brown 2nd, B A; Lin, Y; Roberts, J F et al. (1995) Antibodies specific for the DNA quadruplex [d(CGC G4 GCG)4] isolated from autoimmune mice. Nucleic Acids Symp Ser :134-6
Hardin, C C; Corregan, M; Brown 2nd, B A et al. (1993) Cytosine-cytosine+ base pairing stabilizes DNA quadruplexes and cytosine methylation greatly enhances the effect. Biochemistry 32:5870-80