Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM050009-04
Application #
2187584
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1993-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Physiology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Pasapera, Ana M; Plotnikov, Sergey V; Fischer, Robert S et al. (2015) Rac1-dependent phosphorylation and focal adhesion recruitment of myosin IIA regulates migration and mechanosensing. Curr Biol 25:175-186
Thomas, Dustin G; Yenepalli, Aishwarya; Denais, Celine Marie et al. (2015) Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion. J Cell Biol 210:583-94
Thiagarajan, Praveena S; Hitomi, Masahiro; Hale, James S et al. (2015) Development of a Fluorescent Reporter System to Delineate Cancer Stem Cells in Triple-Negative Breast Cancer. Stem Cells 33:2114-2125
Wessels, Deborah; Lusche, Daniel F; Steimle, Paul A et al. (2012) Myosin heavy chain kinases play essential roles in Ca2+, but not cAMP, chemotaxis and the natural aggregation of Dictyostelium discoideum. J Cell Sci 125:4934-44
Beach, Jordan R; Licate, Lucila S; Crish, James F et al. (2011) Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells. BMC Cell Biol 12:52
Beach, Jordan R; Hussey, George S; Miller, Tyler E et al. (2011) Myosin II isoform switching mediates invasiveness after TGF-?-induced epithelial-mesenchymal transition. Proc Natl Acad Sci U S A 108:17991-6
Rai, Vandana; Egelhoff, Thomas T (2011) Role of B regulatory subunits of protein phosphatase type 2A in myosin II assembly control in Dictyostelium discoideum. Eukaryot Cell 10:604-10
Wang, Yu; Steimle, Paul A; Ren, Yixin et al. (2011) Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation. Mol Biol Cell 22:2270-81
Betapudi, Venkaiah; Egelhoff, Thomas T (2009) Roles of an unconventional protein kinase and myosin II in amoeba osmotic shock responses. Traffic 10:1773-84