Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM050766-03
Application #
2188814
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
Takabayashi, Tsukasa; Shimizu, Soichi; Clark, Burton D et al. (2004) Interleukin-1 upregulates anaphylatoxin receptors on mononuclear cells. Surgery 135:544-54
Takabayashi, T; Vannier, E; Burke, J F et al. (1998) Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells. J Infect Dis 177:1622-8
Aiura, K; Clark, B D; Dinarello, C A et al. (1997) Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells. J Infect Dis 175:123-9
Ge, Y; Ezzell, R M; Clark, B D et al. (1997) Relationship of tissue and cellular interleukin-1 and lipopolysaccharide after endotoxemia and bacteremia. J Infect Dis 176:1313-21
Takabayashi, T; Vannier, E; Clark, B D et al. (1996) A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis. J Immunol 156:3455-60
Clark, B D; Ikejima, T; Mancilla, J et al. (1996) An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding. J Interferon Cytokine Res 16:1079-88
Allen, J B; McGahan, M C; Ogawa, Y et al. (1996) Intravitreal transforming growth factor-beta 2 decreases cellular infiltration in endotoxin-induced ocular inflammation in rabbits. Curr Eye Res 15:95-103