Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM050958-03
Application #
2189193
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1994-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Surgery
Type
Schools of Medicine
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Pham, Tuan H; Hornung, Rene; Ha, Hongphuc P et al. (2002) Noninvasive monitoring of hemodynamic stress using quantitative near-infrared frequency-domain photon migration spectroscopy. J Biomed Opt 7:34-44
Cerussi, A E; Berger, A J; Bevilacqua, F et al. (2001) Sources of absorption and scattering contrast for near-infrared optical mammography. Acad Radiol 8:211-8
Shah, N; Cerussi, A; Eker, C et al. (2001) Noninvasive functional optical spectroscopy of human breast tissue. Proc Natl Acad Sci U S A 98:4420-5
Pham, T H; Hornung, R; Berns, M W et al. (2001) Monitoring tumor response during photodynamic therapy using near-infrared photon-migration spectroscopy. Photochem Photobiol 73:669-77
Holboke, M J; Tromberg, B J; Li, X et al. (2000) Three-dimensional diffuse optical mammography with ultrasound localization in a human subject. J Biomed Opt 5:237-47
Tromberg, B J; Shah, N; Lanning, R et al. (2000) Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy. Neoplasia 2:26-40
Hornung, R; Fehr, M K; Walt, H et al. (2000) PEG-m-THPC-mediated photodynamic effects on normal rat tissues. Photochem Photobiol 72:696-700
Hornung, R; Fehr, M K; Monti-Frayne, J et al. (1999) Minimally-invasive debulking of ovarian cancer in the rat pelvis by means of photodynamic therapy using the pegylated photosensitizer PEG-m-THPC. Br J Cancer 81:631-7
Hornung, R; Fehr, M K; Monti-Frayne, J et al. (1999) Highly selective targeting of ovarian cancer with the photosensitizer PEG-m-THPC in a rat model. Photochem Photobiol 70:624-9
Hornung, R; Pham, T H; Keefe, K A et al. (1999) Quantitative near-infrared spectroscopy of cervical dysplasia in vivo. Hum Reprod 14:2908-16

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