Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM052072-02
Application #
2190960
Study Section
Genetics Study Section (GEN)
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wadsworth Center
Department
Type
DUNS #
110521739
City
Menands
State
NY
Country
United States
Zip Code
12204
Qu, Guosheng; Dong, Xiaolong; Piazza, Carol Lyn et al. (2014) RNA-RNA interactions and pre-mRNA mislocalization as drivers of group II intron loss from nuclear genomes. Proc Natl Acad Sci U S A 111:6612-7
Doh, Jung H; Lutz, Sheila; Curcio, M Joan (2014) Co-translational localization of an LTR-retrotransposon RNA to the endoplasmic reticulum nucleates virus-like particle assembly sites. PLoS Genet 10:e1004219
Maxwell, Patrick H; Burhans, William C; Curcio, M Joan (2011) Retrotransposition is associated with genome instability during chronological aging. Proc Natl Acad Sci U S A 108:20376-81
Belfort, Marlene; Curcio, M Joan; Lue, Neal F (2011) Telomerase and retrotransposons: reverse transcriptases that shaped genomes. Proc Natl Acad Sci U S A 108:20304-10
Bairwa, Narendra K; Mohanty, Bidyut K; Stamenova, Radostina et al. (2011) The intra-S phase checkpoint protein Tof1 collaborates with the helicase Rrm3 and the F-box protein Dia2 to maintain genome stability in Saccharomyces cerevisiae. J Biol Chem 286:2445-54
Dutko, James A; Kenny, Alison E; Gamache, Eric R et al. (2010) 5' to 3' mRNA decay factors colocalize with Ty1 gag and human APOBEC3G and promote Ty1 retrotransposition. J Virol 84:5052-66
Stamenova, Radostina; Maxwell, Patrick H; Kenny, Alison E et al. (2009) Rrm3 protects the Saccharomyces cerevisiae genome from instability at nascent sites of retrotransposition. Genetics 182:711-23