Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM052483-02
Application #
2191528
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1995-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Texas A&M University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
College Station
State
TX
Country
United States
Zip Code
77845
Nick Pace, C; Scholtz, J Martin; Grimsley, Gerald R (2014) Forces stabilizing proteins. FEBS Lett 588:2177-84
Pace, C Nick; Fu, Hailong; Lee Fryar, Katrina et al. (2014) Contribution of hydrogen bonds to protein stability. Protein Sci 23:652-61
Pace, C Nick; Fu, Hailong; Fryar, Katrina Lee et al. (2011) Contribution of hydrophobic interactions to protein stability. J Mol Biol 408:514-28
Fu, Hailong; Grimsley, Gerald; Scholtz, J Martin et al. (2010) Increasing protein stability: importance of DeltaC(p) and the denatured state. Protein Sci 19:1044-52
Nick Pace, C; Huyghues-Despointes, Beatrice M P; Fu, Hailong et al. (2010) Urea denatured state ensembles contain extensive secondary structure that is increased in hydrophobic proteins. Protein Sci 19:929-43
Grimsley, Gerald R; Scholtz, J Martin; Pace, C Nick (2009) A summary of the measured pK values of the ionizable groups in folded proteins. Protein Sci 18:247-51
Scholtz, J Martin; Grimsley, Gerald R; Pace, C Nick (2009) Solvent denaturation of proteins and interpretations of the m value. Methods Enzymol 466:549-65
Fu, Hailong; Grimsley, Gerald R; Razvi, Abbas et al. (2009) Increasing protein stability by improving beta-turns. Proteins 77:491-8
Smith, J S; Scholtz, J M (1996) Guanidine hydrochloride unfolding of peptide helices: separation of denaturant and salt effects. Biochemistry 35:7292-7
Thapar, R; Nicholson, E M; Rajagopal, P et al. (1996) Influence of N-cap mutations on the structure and stability of Escherichia coli HPr. Biochemistry 35:11268-77

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