Signal Transduction of A G Protein Coupled Receptor

Kuliopulos, Athan

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29GM052926-02
• Application #: 2192133
• Study Section: Cellular Biology and Physiology Subcommittee 1 (CBY)
• Project Start: 1995-08-01
• Project End: 2000-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: Tufts University
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02111

Publications

Swift, S; Sheridan, P J; Covic, L et al. (2000) PAR1 thrombin receptor-G protein interactions. Separation of binding and coupling determinants in the galpha subunit. J Biol Chem 275:2627-35

Kuliopulos, A; Covic, L; Seeley, S K et al. (1999) Plasmin desensitization of the PAR1 thrombin receptor: kinetics, sites of truncation, and implications for thrombolytic therapy. Biochemistry 38:4572-85