Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29GM056615-01
Application #
2429049
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1997-08-01
Project End
1997-08-31
Budget Start
1997-08-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Creighton University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68178
Tabah, Azah A; Tardif, Keith; Mansky, Louis M (2014) Anti-HIV-1 activity of Trim 37. J Gen Virol 95:960-7
Guenzel, Carolin A; Herate, Cecile; Le Rouzic, Erwann et al. (2012) Recruitment of the nuclear form of uracil DNA glycosylase into virus particles participates in the full infectivity of HIV-1. J Virol 86:2533-44
Clouser, Christine L; Chauhan, Jay; Bess, Matthew A et al. (2012) Anti-HIV-1 activity of resveratrol derivatives and synergistic inhibition of HIV-1 by the combination of resveratrol and decitabine. Bioorg Med Chem Lett 22:6642-6
Clouser, Christine L; Holtz, Colleen M; Mullett, Mary et al. (2012) Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1. Antimicrob Agents Chemother 56:1942-8
Dorr, Casey R; Yemets, Sergiy; Kolomitsyna, Oksana et al. (2011) Triterpene derivatives that inhibit human immunodeficiency virus type 1 replication. Bioorg Med Chem Lett 21:542-5
Clouser, Christine L; Holtz, Colleen M; Mullett, Mary et al. (2011) Analysis of the ex vivo and in vivo antiretroviral activity of gemcitabine. PLoS One 6:e15840
Grigsby, Iwen F; Pham, Lan; Mansky, Louis M et al. (2010) Tenofovir treatment of primary osteoblasts alters gene expression profiles: implications for bone mineral density loss. Biochem Biophys Res Commun 394:48-53
Clouser, Christine L; Patterson, Steven E; Mansky, Louis M (2010) Exploiting drug repositioning for discovery of a novel HIV combination therapy. J Virol 84:9301-9
Grigsby, Iwen F; Pham, Lan; Gopalakrishnan, Raj et al. (2010) Downregulation of Gnas, Got2 and Snord32a following tenofovir exposure of primary osteoclasts. Biochem Biophys Res Commun 391:1324-9
Dapp, Michael J; Clouser, Christine L; Patterson, Steven et al. (2009) 5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1. J Virol 83:11950-8