Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
3R29HD021961-01S1
Application #
3469334
Study Section
Human Embryology and Development Subcommittee 2 (HED)
Project Start
1986-07-01
Project End
1991-06-30
Budget Start
1987-04-01
Budget End
1987-06-30
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
Earth Sciences/Resources
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Heard, Melissa E; Velarde, Michael C; Giudice, Linda C et al. (2015) Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biol Reprod 92:140
Simmen, Rosalia C M; Heard, Melissa E; Simmen, Angela M et al. (2015) The Krüppel-like factors in female reproductive system pathologies. J Mol Endocrinol 54:R89-R101
Pabona, John Mark P; Zhang, Daying; Ginsburg, David S et al. (2015) Prolonged pregnancy in women is associated with attenuated myometrial expression of progesterone receptor co-regulator Krüppel-like Factor 9. J Clin Endocrinol Metab 100:166-74
Heard, Melissa E; Simmons, Christian D; Simmen, Frank A et al. (2014) Krüppel-like factor 9 deficiency in uterine endometrial cells promotes ectopic lesion establishment associated with activated notch and hedgehog signaling in a mouse model of endometriosis. Endocrinology 155:1532-46
Pabona, John Mark P; Simmen, Frank A; Nikiforov, Mikhail A et al. (2012) Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis. J Clin Endocrinol Metab 97:E376-92
Heard, Melissa E; Pabona, John Mark P; Clayberger, Carol et al. (2012) The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterus. Biol Reprod 87:115
Simmons, Christian D; Pabona, John Mark P; Heard, Melissa E et al. (2011) Krüppel-like factor 9 loss-of-expression in human endometrial carcinoma links altered expression of growth-regulatory genes with aberrant proliferative response to estrogen. Biol Reprod 85:378-85
Simmons, C D; Pabona, J M P; Zeng, Z et al. (2010) Response of adult mouse uterus to early disruption of estrogen receptor-alpha signaling is influenced by Krüppel-like factor 9. J Endocrinol 205:147-57
Simmen, R C M; Pabona, J M P; Velarde, M C et al. (2010) The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues. J Endocrinol 204:223-31
Pabona, J M P; Velarde, M C; Zeng, Z et al. (2009) Nuclear receptor co-regulator Krüppel-like factor 9 and prohibitin 2 expression in estrogen-induced epithelial cell proliferation in the mouse uterus. J Endocrinol 200:63-73