Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29HD034059-01
Application #
2207613
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1996-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Genetics
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Innis, Jeffrey W; Margulies, Elliott H; Kardia, Sharon (2002) Integrative biology and the developing limb bud. Evol Dev 4:378-89
Innis, Jeffrey W; Goodman, Frances R; Bacchelli, Chiara et al. (2002) A HOXA13 allele with a missense mutation in the homeobox and a dinucleotide deletion in the promoter underlies Guttmacher syndrome. Hum Mutat 19:573-4
Margulies, E H; Kardia, S L; Innis, J W (2001) A comparative molecular analysis of developing mouse forelimbs and hindlimbs using serial analysis of gene expression (SAGE). Genome Res 11:1686-98
Post, L C; Margulies, E H; Kuo, A et al. (2000) Severe limb defects in Hypodactyly mice result from the expression of a novel, mutant HOXA13 protein. Dev Biol 217:290-300
Margulies, E H; Innis, J W (2000) eSAGE: managing and analysing data generated with serial analysis of gene expression (SAGE). Bioinformatics 16:650-1
Goodman, F R; Bacchelli, C; Brady, A F et al. (2000) Novel HOXA13 mutations and the phenotypic spectrum of hand-foot-genital syndrome. Am J Hum Genet 67:197-202
Post, L C; Innis, J W (1999) Infertility in adult hypodactyly mice is associated with hypoplasia of distal reproductive structures. Biol Reprod 61:1402-8
Post, L C; Innis, J W (1999) Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice. Int J Dev Biol 43:287-94
Innis, J W; Mortlock, D P (1998) Limb development: molecular dysmorphology is at hand! Clin Genet 53:337-48
Mortlock, D P; Innis, J W (1997) Mutation of HOXA13 in hand-foot-genital syndrome. Nat Genet 15:179-80