Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL039719-05
Application #
3471744
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1989-01-01
Project End
1993-12-31
Budget Start
1993-01-01
Budget End
1993-12-31
Support Year
5
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
White, M; Roden, R; Minobe, W et al. (1994) Age-related changes in beta-adrenergic neuroeffector systems in the human heart. Circulation 90:1225-38
Feldman, A M; Strobeck, J E (1994) Quinolinone derivatives in the management of congestive heart failure. Coron Artery Dis 5:107-11
Williams, R E; Kass, D A; Kawagoe, Y et al. (1994) Endomyocardial gene expression during development of pacing tachycardia-induced heart failure in the dog. Circ Res 75:615-23
Farrukh, H M; White, M; Port, J D et al. (1993) Up-regulation of beta 2-adrenergic receptors in previously transplanted, denervated nonfailing human hearts. J Am Coll Cardiol 22:1902-8
Feldman, A M; Weinberg, E O; Ray, P E et al. (1993) Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. Circ Res 73:184-92
Feldman, A M (1993) Modulation of adrenergic receptors and G-transduction proteins in failing human ventricular myocardium. Circulation 87:IV27-34
Bristow, M R; Minobe, W A; Raynolds, M V et al. (1993) Reduced beta 1 receptor messenger RNA abundance in the failing human heart. J Clin Invest 92:2737-45
Ladenson, P W; Sherman, S I; Baughman, K L et al. (1992) Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism. Proc Natl Acad Sci U S A 89:5251-5
Johns, D C; Feldman, A M (1992) Identification of a highly conserved region at the 5' flank of the phospholamban gene. Biochem Biophys Res Commun 188:927-33
Feldman, A M; Ray, P E; Silan, C M et al. (1991) Selective gene expression in failing human heart. Quantification of steady-state levels of messenger RNA in endomyocardial biopsies using the polymerase chain reaction. Circulation 83:1866-72

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