Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
7R29HL045136-05
Application #
3473223
Study Section
Pathology A Study Section (PTHA)
Project Start
1990-07-01
Project End
1995-06-30
Budget Start
1993-12-01
Budget End
1994-06-30
Support Year
5
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Rush University Medical Center
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612
Gopallawa, Indiwari; Uhal, Bruce D (2016) Angiotensin-(1-7)/mas inhibits apoptosis in alveolar epithelial cells through upregulation of MAP kinase phosphatase-2. Am J Physiol Lung Cell Mol Physiol 310:L240-8
Mohamed, Tarek L; Nguyen, Hang T; Abdul-Hafez, Amal et al. (2016) Prior hypoxia prevents downregulation of ACE-2 by hyperoxia in fetal human lung fibroblasts. Exp Lung Res 42:121-30
Oarhe, Chinyere I; Dang, Vinh; Dang, MyTrang et al. (2015) Hyperoxia downregulates angiotensin-converting enzyme-2 in human fetal lung fibroblasts. Pediatr Res 77:656-62
Dang, My-Trang T; Gu, Chenyang; Klavanian, Jeannie I et al. (2013) Angiotensinogen promoter polymorphisms predict low diffusing capacity in U.S. and Spanish IPF cohorts. Lung 191:353-60
Uhal, Bruce D; Dang, MyTrang; Dang, Vinh et al. (2013) Cell cycle dependence of ACE-2 explains downregulation in idiopathic pulmonary fibrosis. Eur Respir J 42:198-210
Uhal, Bruce D; Nguyen, Hang; Dang, MyTrang et al. (2013) Abrogation of ER stress-induced apoptosis of alveolar epithelial cells by angiotensin 1-7. Am J Physiol Lung Cell Mol Physiol 305:L33-41
Uhal, Bruce D; Nguyen, Hang (2013) The Witschi Hypothesis revisited after 35 years: genetic proof from SP-C BRICHOS domain mutations. Am J Physiol Lung Cell Mol Physiol 305:L906-11
Uhal, Bruce D; Li, Xiaopeng; Xue, Anita et al. (2011) Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1-7/Mas axis. Am J Physiol Lung Cell Mol Physiol 301:L269-74
Abdul-Hafez, Amal; Shu, Ruijie; Uhal, Bruce D (2009) JunD and HIF-1alpha mediate transcriptional activation of angiotensinogen by TGF-beta1 in human lung fibroblasts. FASEB J 23:1655-62