Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL046865-03
Application #
3473576
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1991-08-01
Project End
1996-07-31
Budget Start
1993-08-01
Budget End
1994-07-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of New Mexico
Department
Type
Schools of Medicine
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Song, W; Jackson, K; McGuire, P G (2000) Degradation of type IV collagen by matrix metalloproteinases is an important step in the epithelial-mesenchymal transformation of the endocardial cushions. Dev Biol 227:606-17
Song, W; Majka, S M; McGuire, P G (1999) Hepatocyte growth factor expression in the developing myocardium: evidence for a role in the regulation of the mesenchymal cell phenotype and urokinase expression. Dev Dyn 214:92-100
Alexander, S M; Jackson, K J; Bushnell, K M et al. (1997) Spatial and temporal expression of the 72-kDa type IV collagenase (MMP-2) correlates with development and differentiation of valves in the embryonic avian heart. Dev Dyn 209:261-8
Majka, S M; McGuire, P G (1997) Regulation of urokinase expression in the developing avian heart: a role for the Ets-2 transcription factor. Mech Dev 68:127-37
Walker-Caprioglio, H M; Hunter, D D; McGuire, P G et al. (1995) Composition in situ and in vitro of vascular smooth muscle laminin in the rat. Cell Tissue Res 281:187-96
Rosenberg, G A; Dencoff, J E; McGuire, P G et al. (1994) Injury-induced 92-kilodalton gelatinase and urokinase expression in rat brain. Lab Invest 71:417-22
Conrad, K P; Vill, M; McGuire, P G et al. (1993) Expression of nitric oxide synthase by syncytiotrophoblast in human placental villi. FASEB J 7:1269-76
McGuire, P G; Walker-Caprioglio, H M; Little, S A et al. (1993) Isolation and culture of rat superior mesenteric artery smooth muscle cells. In Vitro Cell Dev Biol 29A:135-9
McGuire, P G; Alexander, S M (1993) Urokinase production by embryonic endocardial-derived cells: regulation by substrate composition. Dev Biol 155:442-51
McGuire, P G; Alexander, S M (1993) Inhibition of urokinase synthesis and cell surface binding alters the motile behavior of embryonic endocardial-derived mesenchymal cells in vitro. Development 118:931-9

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