Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL050403-03
Application #
2226581
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1994-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Wajima, Z; Hua, X Y; Yaksh, T L (2000) Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesia. Brain Res 877:314-21
Hua, X Y; Chen, P; Marsala, M et al. (1999) Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acids. Neuroscience 89:525-34
Hua, X Y; Chen, P; Yaksh, T L (1999) Inhibition of spinal protein kinase C reduces nerve injury-induced tactile allodynia in neuropathic rats. Neurosci Lett 276:99-102
Hogman, M; Reber, A; Hua, X Y et al. (1998) Effects of endotracheal intubation on airway neuropeptide content, arterial oxygenation and lung volumes in anaesthetized rats. Eur J Clin Invest 28:249-55
Calcutt, N A; Chen, P; Hua, X Y (1998) Effects of diabetes on tissue content and evoked release of calcitonin gene-related peptide-like immunoreactivity from rat sensory nerves. Neurosci Lett 254:129-32
Hua, X Y; Chen, P; Polgar, E et al. (1998) Spinal neurokinin NK1 receptor down-regulation and antinociception: effects of spinal NK1 receptor antisense oligonucleotides and NK1 receptor occupancy. J Neurochem 70:688-98
Hua, X Y; Calcutt, N A; Malmberg, A B (1997) Neonatal capsaicin treatment abolishes formalin-induced spinal PGE2 release. Neuroreport 8:2325-9
Dirig, D M; Hua, X Y; Yaksh, T L (1997) Temperature dependency of basal and evoked release of amino acids and calcitonin gene-related peptide from rat dorsal spinal cord. J Neurosci 17:4406-14
Hua, X Y; Chen, P; Fox, A et al. (1996) Involvement of cytokines in lipopolysaccharide-induced facilitation of CGRP release from capsaicin-sensitive nerves in the trachea: studies with interleukin-1beta and tumor necrosis factor-alpha. J Neurosci 16:4742-8
Hua, X Y; Back, S M; Tam, E K (1996) Substance P enhances electrical field stimulation-induced mast cell degranulation in rat trachea. Am J Physiol 270:L985-91

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