Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29HL056482-01A1
Application #
2234994
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1996-08-01
Project End
2000-06-30
Budget Start
1996-08-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Pathology
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Waldman, W James; LeClaire, Joshua D; Knight, Deborah A (2002) T-cell activation response to allogeneic CMV-infected endothelial cells is not prevented by ganciclovir or foscarnet: implications for transplant vascular sclerosis. Transplantation 73:314-8
Knight, D A; Hejmanowski, A Q; Dierksheide, J E et al. (2001) Inhibition of herpes simplex virus type 1 by the experimental immunosuppressive agent leflunomide. Transplantation 71:170-4
Waldman, W J; Bickerstaff, A; Gordillo, G et al. (2001) Inhibition of angiogenesis-related endothelial activity by the experimental immunosuppressive agent leflunomide. Transplantation 72:1578-82
Knight, D A; Briggs, B R; Bennett, C F et al. (2000) Attenuation of cytomegalovirus-induced endothelial intercellular adhesion molecule-1 mRNA/protein expression and T lymphocyte adhesion by a 2'-O-methoxyethyl antisense oligonucleotide. Transplantation 69:417-26
Waldman, W J; Knight, D A; Blinder, L et al. (1999) Inhibition of cytomegalovirus in vitro and in vivo by the experimental immunosuppressive agent leflunomide. Intervirology 42:412-8
Carrodeguas, L; Orosz, C G; Waldman, W J et al. (1999) Trans vivo analysis of human delayed-type hypersensitivity reactivity. Hum Immunol 60:640-51
Knight, D A; Waldman, W J; Sedmak, D D (1999) Cytomegalovirus-mediated modulation of adhesion molecule expression by human arterial and microvascular endothelial cells. Transplantation 68:1814-8
Waldman, W J; Knight, D A; Lurain, N S et al. (1999) Novel mechanism of inhibition of cytomegalovirus by the experimental immunosuppressive agent leflunomide. Transplantation 68:814-25
Waldman, W J; Knight, D A; Huang, E H (1998) An in vitro model of T cell activation by autologous cytomegalovirus (CMV)-infected human adult endothelial cells: contribution of CMV-enhanced endothelial ICAM-1. J Immunol 160:3143-51
Waldman, W J; Knight, D A; Adams, P W (1998) Cytolytic activity against allogeneic human endothelia: resistance of cytomegalovirus-infected cells and virally activated lysis of uninfected cells. Transplantation 66:67-77