Our hypothesis is that clinical events that have no significant temporal duration, called point events, and events that have relevant temporal duration, called interval events, are essential elements in patient- specific clinical decision making. We describe a six-step research plan based on the premise that current clinical information systems cannot provide context-sensitive data retrieval for two reasons: (1) current data models do not explicitly store interval events, and (2) current query languages cannot specify temporal relationships among point and interval events. Our research plan will collect requests for patient information generated in actual clinical decision-making settings, analyze the temporal and contextual features of these requests, attempt to translate these requests into current database query languages, and study the sources of difficulty or failures in these translations. From this analysis, we propose to define a new data model for explicitly storing point and interval events and a new query language for specifying data retrieval based on relationships among instantaneous and interval events. 1. We will establish a library of context-sensitive medical queries obtained from recorded transcripts of teaching attending rounds in Internal Medicine and expert diabetologists analyzing timed insulin and glucose data in diabetic patient log books. 2. We will translate each query into an unambiguous representation to ensure that all implied or shared clinical events and states are made explicitly in an """"""""gold-standard"""""""" reference for each query. 3. We will translate each query into seven languages that have unique strengths in representing temporal and contextual relationships, analyze the source of difficulties when a translation is not possible, and generate a list of language primitives that must be present to specify time-and context-sensitive medical data retrieval. 4. We will develop a temporal semantic data model and query language that incorporates both point and interval events a primitive database objects. 5. We will implement our data model and query language by extending a commercial relational database system. 6. We will evaluate our temporal database system in a clinical environment.

Agency
National Institute of Health (NIH)
Institute
National Library of Medicine (NLM)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29LM005387-03
Application #
2237783
Study Section
Biomedical Library and Informatics Review Committee (BLR)
Project Start
1992-02-01
Project End
1997-01-31
Budget Start
1994-02-01
Budget End
1995-01-31
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Kahn, M G (1997) Three perspectives on integrated clinical databases. Acad Med 72:281-6
Coble, J M; Karat, J; Orland, M J et al. (1997) Iterative usability testing: ensuring a usable clinical workstation. Proc AMIA Annu Fall Symp :744-8
Graham, M V; Jain, N L; Kahn, M G et al. (1996) Evaluation of an objective plan-evaluation model in the three dimensional treatment of nonsmall cell lung cancer. Int J Radiat Oncol Biol Phys 34:469-74
Kahn, M G; Bailey, T C; Steib, S A et al. (1996) Statistical process control methods for expert system performance monitoring. J Am Med Inform Assoc 3:258-69
Kahn, M G; Steib, S A; Dunagan, W C et al. (1996) Monitoring expert system performance using continuous user feedback. J Am Med Inform Assoc 3:216-23
Kahn, M G; Steib, S A; Spitznagel, E L et al. (1995) Improvement in user performance following development and routine use of an expert system. Medinfo 8 Pt 2:1064-7
Kahn, M G (1995) The computer-based patient record and Robert Fulghum's 16 principles. MD Comput 12:253-8
Kahn, M G; Marrs, K A (1995) Creating temporal abstractions in three clinical information systems. Proc Annu Symp Comput Appl Med Care :392-6
Murphy, J F; Kahn, M G; Krone, R J (1995) Prethrombolytic versus thrombolytic era risk stratification of patients with acute myocardial infarction. Am J Cardiol 76:827-9
Marrs, K A; Kahn, M G (1995) Extending a clinical repository to include multiple sites. Proc Annu Symp Comput Appl Med Care :387-91

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