Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29MH048381-05
Application #
2033882
Study Section
Biological Psychopathology Review Committee (BPP)
Project Start
1992-09-30
Project End
1997-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Psychiatry
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Swerdlow, N R; Zisook, D; Taaid, N (1994) Seroquel (ICI 204,636) restores prepulse inhibition of acoustic startle in apomorphine-treated rats: Similarities to clozapine. Psychopharmacology (Berl) 114:675-8
Kodsi, M H; Swerdlow, N R (1994) Quinolinic acid lesions of the ventral striatum reduce sensorimotor gating of acoustic startle in rats. Brain Res 643:59-65
Swerdlow, N R; Britton, K T (1994) Alphaxalone, a steroid anesthetic, inhibits the startle-enhancing effects of corticotropin releasing factor, but not strychnine. Psychopharmacology (Berl) 115:141-6
Swerdlow, N R; Braff, D L; Taaid, N et al. (1994) Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch Gen Psychiatry 51:139-54
Bakshi, V P; Swerdlow, N R; Geyer, M A (1994) Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response. J Pharmacol Exp Ther 271:787-94
Wan, F J; Geyer, M A; Swerdlow, N R (1994) Accumbens D2 modulation of sensorimotor gating in rats: assessing anatomical localization. Pharmacol Biochem Behav 49:155-63
Wan, F J; Swerdlow, N R (1993) Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats. Psychopharmacology (Berl) 113:103-9
Swerdlow, N R; Geyer, M A (1993) Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia. Pharmacol Biochem Behav 44:741-4
Swerdlow, N R; Auerbach, P; Monroe, S M et al. (1993) Men are more inhibited than women by weak prepulses. Biol Psychiatry 34:253-60