Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS024694-05
Application #
3476794
Study Section
Neurology C Study Section (NEUC)
Project Start
1987-07-01
Project End
1992-06-30
Budget Start
1991-07-01
Budget End
1992-06-30
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
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McCormick, D J; Liebenow, J A; Griesmann, G E et al. (1993) Nine residues influence the binding of alpha-bungarotoxin in alpha-subunit region 185-200 of human muscle acetylcholine receptor. J Neurochem 60:1906-14
Sano, M; Lambert, E H; McCormick, D J et al. (1992) Muscle acetylcholine receptors complexed with autologous IgG reflect seropositivity but not necessarily in vivo binding. Neurology 42:218-22
Griesmann, G E; McCormick, D J; Lennon, V A (1991) An avidin-biotin-peroxidase assay to detect synthetic peptides bound to polystyrene plates. J Immunol Methods 138:25-9
Sano, M; McCormick, D J; Talib, S et al. (1991) Identification of three extended antibody-binding segments in recombinant human muscle acetylcholine receptor alpha subunit extracellular domain 1-210. Int Immunol 3:983-9
Griesmann, G E; McCormick, D J; De Aizpurua, H J et al. (1990) Alpha-bungarotoxin binds to human acetylcholine receptor alpha-subunit peptide 185-199 in solution and solid phase but not to peptides 125-147 and 389-409. J Neurochem 54:1541-7
McCormick, D J; Hillman, K; David, C S (1988) Production of antibodies against murine class II antigens using unconjugated synthetic peptides of the beta chain region 63-78. J Immunol Methods 113:165-74
Lennon, V A; Huang, Z X; McCormick, D J et al. (1988) Synthetic peptide of human acetylcholine receptor alpha-subunit sequence 125-147 (methionine 144), a more potent autoantigen than its norleucine 144 analog. Ann N Y Acad Sci 540:516-9
McCormick, D J; Griesmann, G E; Huang, Z X et al. (1987) Myasthenogenicity of human acetylcholine receptor synthetic alpha-subunit peptide 125-147 does not require intramolecular disulfide cyclization. J Immunol 139:2615-9