Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS026125-06
Application #
3477385
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1988-04-01
Project End
1992-09-27
Budget Start
1992-04-01
Budget End
1992-09-27
Support Year
6
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Good Samaritan Hosp & Medical Center(Prtlnd,OR)
Department
Type
DUNS #
City
Portland
State
OR
Country
United States
Zip Code
97210
Nagasaka, S; Tanabe, K K; Bruner, J M et al. (1995) Alternative RNA splicing of the hyaluronic acid receptor CD44 in the normal human brain and in brain tumors. J Neurosurg 82:858-63
Morrison, R S; Yamaguchi, F; Bruner, J M et al. (1994) Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme. Cancer Res 54:2794-9
Yamaguchi, F; Saya, H; Bruner, J M et al. (1994) Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas. Proc Natl Acad Sci U S A 91:484-8
Morrison, R S; Shi, E; Kan, M et al. (1994) Inositolhexakisphosphate (InsP6): an antagonist of fibroblast growth factor receptor binding and activity. In Vitro Cell Dev Biol Anim 30A:783-9
Sherman, L; Stocker, K M; Morrison, R et al. (1993) Basic fibroblast growth factor (bFGF) acts intracellularly to cause the transdifferentiation of avian neural crest-derived Schwann cell precursors into melanocytes. Development 118:1313-26
Morrison, R S; Giordano, S; Yamaguchi, F et al. (1993) Basic fibroblast growth factor expression is required for clonogenic growth of human glioma cells. J Neurosci Res 34:502-9
Chalazonitis, A; Kessler, J A; Twardzik, D R et al. (1992) Transforming growth factor alpha, but not epidermal growth factor, promotes the survival of sensory neurons in vitro. J Neurosci 12:583-94
Giordano, S; Sherman, L; Lyman, W et al. (1992) Multiple molecular weight forms of basic fibroblast growth factor are developmentally regulated in the central nervous system. Dev Biol 152:293-303
Chalazonitis, A; Kalberg, J; Twardzik, D R et al. (1992) Transforming growth factor beta has neurotrophic actions on sensory neurons in vitro and is synergistic with nerve growth factor. Dev Biol 152:121-32
Morrison, R S (1991) Suppression of basic fibroblast growth factor expression by antisense oligodeoxynucleotides inhibits the growth of transformed human astrocytes. J Biol Chem 266:728-34

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