Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
3R29NS031718-04S1
Application #
2269671
Study Section
Neurology A Study Section (NEUA)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1996-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Sun, Hongyu; Juul, Halvor M; Jensen, Frances E (2016) Models of hypoxia and ischemia-induced seizures. J Neurosci Methods 260:252-60
Jantzie, Lauren L; Hu, Melody Y; Park, Hyun-Kyung et al. (2015) Chloride cotransporter NKCC1 inhibitor bumetanide protects against white matter injury in a rodent model of periventricular leukomalacia. Pediatr Res 77:554-62
Jantzie, Lauren L; Talos, Delia M; Jackson, Michele C et al. (2015) Developmental expression of N-methyl-D-aspartate (NMDA) receptor subunits in human white and gray matter: potential mechanism of increased vulnerability in the immature brain. Cereb Cortex 25:482-95
Loddenkemper, Tobias; Talos, Delia M; Cleary, Ryan T et al. (2014) Subunit composition of glutamate and gamma-aminobutyric acid receptors in status epilepticus. Epilepsy Res 108:605-15
Cleary, Ryan T; Sun, Hongyu; Huynh, Thanhthao et al. (2013) Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures. PLoS One 8:e57148
Talos, Delia M; Chang, Meayoung; Kosaras, Bela et al. (2013) Antiepileptic effects of levetiracetam in a rodent neonatal seizure model. Pediatr Res 73:24-30
Lippman-Bell, Jocelyn J; Rakhade, Sanjay N; Klein, Peter M et al. (2013) AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures. Epilepsia 54:1922-32
Theilhaber, Joachim; Rakhade, Sanjay N; Sudhalter, Judy et al. (2013) Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis. PLoS One 8:e74428
Rakhade, Sanjay N; Fitzgerald, Erin F; Klein, Peter M et al. (2012) Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. J Neurosci 32:17800-12
Talos, Delia M; Sun, Hongyu; Kosaras, Bela et al. (2012) Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. Ann Neurol 71:539-51

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