Catecholamine Regulation in Genetically Modified Grafts

Kang, Un Jung

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29NS032080-04
• Application #: 2270056
• Study Section: Neurology B Subcommittee 2 (NEUB)
• Project Start: 1993-08-01
• Project End: 1998-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Chicago
• Department: Neurology
• Type: Schools of Medicine
• DUNS #: 225410919
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60637

Publications

Chang, J W; Wachtel, S R; Young, D et al. (1999) Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions. Neuroscience 88:617-28

Wachtel, S R; Bencsics, C; Kang, U J (1997) Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease. J Neurochem 69:2055-63

Bencsics, C; Wachtel, S R; Milstien, S et al. (1996) Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts. J Neurosci 16:4449-56

Levivier, M; Przedborski, S; Bencsics, C et al. (1995) Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. J Neurosci 15:7810-20