Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS032283-02
Application #
2270341
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1995-08-15
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Neurology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Stout, Charles E; Costantin, James L; Naus, Christian C G et al. (2002) Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels. J Biol Chem 277:10482-8
Costantin, J L; Charles, A C (2001) Modulation of Ca(2+) signaling by K(+) channels in a hypothalamic neuronal cell line (GT1-1). J Neurophysiol 85:295-304
Piros, E T; Charles, R C; Song, L et al. (2000) Cloned delta-opioid receptors in GH(3) cells inhibit spontaneous Ca(2+) oscillations and prolactin release through K(IR) channel activation. J Neurophysiol 83:2691-8
Vitalis, E A; Costantin, J L; Tsai, P S et al. (2000) Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells. Proc Natl Acad Sci U S A 97:1861-6
Costantin, J L; Charles, A C (1999) Spontaneous action potentials initiate rhythmic intercellular calcium waves in immortalized hypothalamic (GT1-1) neurons. J Neurophysiol 82:429-35
Charles, A C; Piros, E T; Evans, C J et al. (1999) L-type Ca2+ channels and K+ channels specifically modulate the frequency and amplitude of spontaneous Ca2+ oscillations and have distinct roles in prolactin release in GH3 cells. J Biol Chem 274:7508-15
Charles, A (1998) Intercellular calcium waves in glia. Glia 24:39-49
Bronstein, J M; Hales, T G; Tyndale, R F et al. (1998) A conditionally immortalized glial cell line that expresses mature myelin proteins and functional GABA(A) receptors. J Neurochem 70:483-91
Harris-White, M E; Zanotti, S A; Frautschy, S A et al. (1998) Spiral intercellular calcium waves in hippocampal slice cultures. J Neurophysiol 79:1045-52
Zanotti, S; Charles, A (1997) Extracellular calcium sensing by glial cells: low extracellular calcium induces intracellular calcium release and intercellular signaling. J Neurochem 69:594-602

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